Publications

Roger M. Pallares, David Faulkner, Dahlia D. An, Solene Hebert, Alex Loguinov, Michael Proctor, Jonathan A. Villalobos, Kathleen A. Bjornstad, Chris J. Rosen, Christopher Vulpe, Rebecca J. Abergel (2021). Genome-wide toxicogenomic study of the lanthanides sheds light on the selective toxicity mechanisms associated with critical materials. Proceedings of the National Academy of Sciences.

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Korey P. Carter, Katherine M. Shield, Kurt F. Smith, Zachary R. Jones, Jennifer N. Wacker, Leticia Arnedo-Sanchez, Tracy M. Mattox, Liane M. Moreau, Karah E. Knope, Stosh A. Kozimor, Corwin H. Booth, Rebecca J. Abergel (2021). Structural and spectroscopic characterization of an einsteinium complex. Nature.

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Gauthier J.P. Deblonde, Trevor D. Lohrey, Dahlia D. An, Rebecca J. Abergel (2018). Toxic heavy metal – Pb, Cd, Sn – complexation by the octadentate hydroxypyridinonate ligand archetype 3,4,3-LI(1,2-HOPO). New Journal of Chemistry.

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Julian A. Rees, Gauthier J.-P. Deblonde, Dahlia D. An, Camille Ansoborlo, Stacey S. Gauny, Rebecca J. Abergel (2018). Evaluating the potential of chelation therapy to prevent and treat gadolinium deposition from MRI contrast agents. Scientific Reports.

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Dahlia D. An, Birgitta Kullgren, Erin E. Jarvis, Rebecca J. Abergel (2017). From early prophylaxis to delayed treatment: Establishing the plutonium decorporation activity window of hydroxypyridinonate chelating agents. Chemico-Biological Interactions.

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Taylor A. Choi, Anna M. Furimsky, Robert Swezey, Deborah I. Bunin, Patricia Byrge, Lalitha V. Iyer, Polly Y. Chang, Rebecca J. Abergel (2015). In Vitro Metabolism and Stability of the Actinide Chelating Agent 3,4,3-LI(1,2-HOPO). Journal of Pharmaceutical Sciences.

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Taylor A. Choi, Aaron N. Endsley, Deborah I. Bunin, Christophe Colas, Dahlia D. An, Joel A. Morales-Rivera, Jonathan A. Villalobos, Walter M. Shinn, Jack E. Dabbs, Polly Y. Chang, Rebecca J. Abergel (2015). Biodistribution of the Multidentate Hydroxypyridinonate Ligand [ 14 C]-3,4,3-LI(1,2-HOPO), a Potent Actinide Decorporation Agent. Drug Development Research.

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Manuel Sturzbecher-Hoehne, Taylor A. Choi, Rebecca J. Abergel (2015). Hydroxypyridinonate Complex Stability of Group (IV) Metals and Tetravalent f-Block Elements: The Key to the Next Generation of Chelating Agents for Radiopharmaceuticals. Inorganic Chemistry.

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Dahlia D An, Jonathan A Villalobos, Joel A Morales-Rivera, Chris J Rosen, Kathleen A. Bjornstad, Stacey S Gauny, Taylor A Choi, Manuel Sturzbecher-Hoehne, Rebecca J Abergel (2014). 238 Pu elimination profiles after delayed treatment with 3,4,3LI(1,2HOPO) in female and male Swiss-Webster mice. International Journal of Radiation Biology.

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Polly Y. Chang, Deborah I. Bunin, Jason Gow, Robert Swezey, Walter Shinn, David K. Shuh, Rebecca J. Abergel (2013). Analytical Methods for the Bioavailability Evaluation of Hydroxypyridinonate Actinide Decorporation Agents in Pre-Clinical Pharmacokinetic Studies. Journal of Chromatography & Separation Techniques.

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Gauthier J-P. Deblonde, Manuel Sturzbecher-Hoehne, Rebecca J Abergel (2013). Solution Thermodynamic Stability of Complexes Formed with the Octadentate Hydroxypyridinonate Ligand 3,4,3-LI(1,2-HOPO): A Critical Feature for Efficient Chelation of Lanthanide(IV) and Actinide(IV) Ions. Inorganic Chemistry.

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Deborah I Bunin, Polly Y Chang, Rupa S Doppalapudi, Edward S Riccio, Dahlia An, Erin E Jarvis, Birgitta Kullgren, Rebecca J Abergel (2013). Dose-dependent efficacy and safety toxicology of hydroxypyridinonate actinide decorporation agents in rodents: towards a safe and effective human dosing regimen.. Radiation research.

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Manuel Sturzbecher-Hoehne, Clara Ng Pak Leung, Anthony D’Aléo, Birgitta Kullgren, Anne-Laure Prigent, David K Shuh, Kenneth N Raymond, Rebecca J Abergel (2011). 3,4,3-LI(1,2-HOPO): In vitro formation of highly stable lanthanide complexes translates into efficacious in vivo europium decorporation. Dalton Transactions.

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Rebecca J. Abergel, Patricia W. Durbin, Birgitta Kullgren, Shirley N. Ebbe, Jide Xu, Polly Y. Chang, Deborah I. Bunin, Eleanor A. Blakely, Kathleen A. Bjornstad, Chris J. Rosen, David K. Shuh, Kenneth N. Raymond (2010). Biomimetic Actinide Chelators: An Update on the Preclinical Development of the Orally Active Hydroxypyridonate Decorporation Agents 3,4,3-LI(1,2-HOPO) and 5-LIO(Me-3,2-HOPO). Health Physics.

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P W Durbin, B Kullgren, J Xu, K N Raymond (2000). Multidentate hydroxypyridinonate ligands for Pu(IV) chelation in vivo: comparative efficacy and toxicity in mouse of ligands containing 1,2-HOPO or Me-3,2-HOPO.. International journal of radiation biology.

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P.W. Durbin, B. Kullgren, J. Xu, K.N. Raymond (1994). In Vivo Chelation of Am(III), Pu(IV), Np(V), and U(VI) in Mice by TREN-(Me-3,2-HOPO). Radiation Protection Dosimetry.

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V. Volf, R. Burgada, K. N. Raymond, P. W. Durbin (1993). Early chelation therapy for injected pu-238 and am-241 in the rat: Comparison of 3,4,3-LIHOPO, DFO-HOPO, DTPA-DX, DTPA and DFOA. International Journal of Radiation Biology.

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G. N. Stradling, S. A. Gray, J. C. Moody, M. J. Pearce, I. Wilson, R. Burgada, T. Bailly, Y. Leroux, K. N. Raymond, P. W. Durbin (1993). Comparative efficacies of 3,4,3-LIHOPO and DTPA for enhancing the excretion of plutonium and americium from the rat after simulated wound contamination as nitrates. International Journal of Radiation Biology.

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